Biography

Professor of Rheumatology at Lille University Hospital, France. He received his MD from Lille University Hospital in 2008. He has prepared and obtained his PhD thesis in 2013 on Vascular Calcification in Rheumatoid Arthritis in the INSERM U1088 laboratory at Amiens University Hospital, France. Then, he completed his postdoctoral fellowship in 2014 at the MRC Lifecourse Epidemiology Unit, University of Southampton, UK under the supervision of Professor Cyrus Cooper.

His recent research has examined Vascular Calcification in Rheumatoid Arthritis. In a review recently published in JCEM, Pr Paccou and colleagues describe the role of the Bone Marrow Fat in Skeletal Health. One of his current projects is assessing body composition changes under ustekinumab among patients with psoriatic arthritis.

Further, Pr Paccou would like to initiate a research project evaluating the bone marrow fat content in postmenopausal women with and without fragility fracture.

List of 5 Best Publications

• Bone Marrow Adiposity Alterations in Postmenopausal Women With Type 2 Diabetes Are Site-Specific

  https://pubmed.ncbi.nlm.nih.gov/39381685/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Conservative Treatments in the Management of Acute Painful Vertebral Compression Fractures: A Systematic Review and Network Meta-Analysis

  https://pubmed.ncbi.nlm.nih.gov/39240564/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Bone Microarchitecture in Older Men with Type 2 Diabetes: The Importance of Bone Size

  https://pubmed.ncbi.nlm.nih.gov/39238334/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Bone health in adults with obesity before and after interventions to promote weight loss

  https://pubmed.ncbi.nlm.nih.gov/39053479/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Romosozumab versus parathyroid hormone receptor agonists: which osteoanabolic to choose and when?

  https://pubmed.ncbi.nlm.nih.gov/38938063/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Response to Pan et al

  https://pubmed.ncbi.nlm.nih.gov/38630875/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Impact of osteoporosis and osteoporosis medications on fracture healing: a narrative review

  https://pubmed.ncbi.nlm.nih.gov/38587674/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Bone mineral density T-scores comparison between obese and non-obese individuals included in a Fracture Liaison Service following a recent fragility fracture

  https://pubmed.ncbi.nlm.nih.gov/38520592/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Proton pump inhibitors, bone and phosphocalcic metabolism

  https://pubmed.ncbi.nlm.nih.gov/38458487/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• A novel deep learning method for large-scale analysis of bone marrow adiposity using UK Biobank Dixon MRI data

  https://pubmed.ncbi.nlm.nih.gov/38268780/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Characteristics of difficult-to-treat axial spondyloarthritis: Results of a real-world multicentric study

  https://pubmed.ncbi.nlm.nih.gov/38036061/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Narrative Review of Effects of Glucagon-Like Peptide-1 Receptor Agonists on Bone Health in People Living with Obesity

  https://pubmed.ncbi.nlm.nih.gov/37999750/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• The Impact of Interventional Weight Loss on Bone Marrow Adipose Tissue in People Living with Obesity and Its Connection to Bone Metabolism

  https://pubmed.ncbi.nlm.nih.gov/37960254/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Association between sarcopenia and risk of major adverse cardiac and cerebrovascular events-UK Biobank database

  https://pubmed.ncbi.nlm.nih.gov/37945290/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Characteristics Of Difficult-To-Treat Psoriatic Arthritis: A Comparative Analysis

  https://pubmed.ncbi.nlm.nih.gov/37852155/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Similarities and Differences in the Management of Patients with Osteoporotic Vertebral Fractures and Those with Rebound-Associated Vertebral Fractures Following Discontinuation of Denosumab

  https://pubmed.ncbi.nlm.nih.gov/37762815/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Glucocorticoid-induced osteoporosis: an overview with focus on its prevention and management

  https://pubmed.ncbi.nlm.nih.gov/37755658/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Relationship between bone marrow adipose tissue and kidney function in postmenopausal women

  https://pubmed.ncbi.nlm.nih.gov/37711545/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Association Between Sarcopenia and Fracture Risk in a Population From the UK Biobank Database

  https://pubmed.ncbi.nlm.nih.gov/37458535/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Myosteatosis and bone marrow adiposity are not associated among postmenopausal women with fragility fractures

  https://pubmed.ncbi.nlm.nih.gov/37404309/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Risk and management of osteoporosis due to inhaled, epidural, intra-articular or topical glucocorticoids

  https://pubmed.ncbi.nlm.nih.gov/37399940/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Usefulness of 18F-Fluorodeoxyglucose Positron Emission Tomography in Diagnosing Polymyalgia Rheumatica and Large-Vessel Vasculitis: A Case-Control Study

  https://pubmed.ncbi.nlm.nih.gov/37109181/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Effectiveness of fracture liaison services in osteoporosis

  https://pubmed.ncbi.nlm.nih.gov/37080285/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Bone Marrow Adiposity and Fragility Fractures in Postmenopausal Women: The ADIMOS Case-Control Study

  https://pubmed.ncbi.nlm.nih.gov/37017011/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Relationships between Circulating Sclerostin, Bone Marrow Adiposity, Other Adipose Deposits and Lean Mass in Post-Menopausal Women

  https://pubmed.ncbi.nlm.nih.gov/36982995/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• An Evaluation of the Implementation of the European Calcified Tissue Society Recommendations on the Prevention and Treatment of Osteoporosis Secondary to Bariatric Surgery

  https://pubmed.ncbi.nlm.nih.gov/36839365/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Frequency and determinants of surgical treatment in patients with uncomplicated disc-related sciatica hospitalized in the Rheumatology Department of Lille University Hospital

  https://pubmed.ncbi.nlm.nih.gov/36605997/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Dietary recommendations in the prevention and treatment of osteoporosis

  https://pubmed.ncbi.nlm.nih.gov/36566976/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Osteoporosis and Bone Marrow Adipose Tissue

  https://pubmed.ncbi.nlm.nih.gov/36534306/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• The Economic Burden of Severe Osteoporotic Fractures in the French Healthcare Database: The FRACTOS Study

  https://pubmed.ncbi.nlm.nih.gov/36203366/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• French recommendations on the prevention and treatment of osteoporosis secondary to bariatric surgery

  https://pubmed.ncbi.nlm.nih.gov/35908644/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Stimulatory Effect of Tofacitinib on Bone Marrow Adipocytes Differentiation

  https://pubmed.ncbi.nlm.nih.gov/35873000/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Subchondral involvement in osteonecrosis of the femoral head: insight on local composition, microstructure and vascularization

  https://pubmed.ncbi.nlm.nih.gov/35568111/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Do vegans have a higher fracture risk?

  https://pubmed.ncbi.nlm.nih.gov/35093612/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• A retrospective study on the etiological exploration of osteoporosis in aging men in a French geriatric setting

  https://pubmed.ncbi.nlm.nih.gov/35065921/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• The global approach to rehabilitation following an osteoporotic fragility fracture: A review of the rehabilitation working group of the International Osteoporosis Foundation (IOF) committee of scientific advisors

  https://pubmed.ncbi.nlm.nih.gov/35048200/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• A comparison of changes in bone turnover markers after gastric bypass and sleeve gastrectomy, and their association with markers of interest

  https://pubmed.ncbi.nlm.nih.gov/34973928/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Analysis of Hip Fractures in France During the First COVID-19 Lockdown in Spring 2020

  https://pubmed.ncbi.nlm.nih.gov/34787657/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Bariatric surgery and skeletal health: A narrative review and position statement for management by the European Calcified Tissue Society (ECTS)

  https://pubmed.ncbi.nlm.nih.gov/34688942/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Refracture and mortality following hospitalization for severe osteoporotic fractures: The Fractos Study

  https://pubmed.ncbi.nlm.nih.gov/34258503/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Body composition in patients with rheumatoid arthritis: a narrative literature review

  https://pubmed.ncbi.nlm.nih.gov/34221129/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Body Composition in Patients With Psoriatic Arthritis and Changes During Interleukin-12/Interleukin-23 Inhibition

  https://pubmed.ncbi.nlm.nih.gov/33973385/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Fracture liaison services: systematic approach to secondary fracture prevention

  https://pubmed.ncbi.nlm.nih.gov/33739768/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• The French multicentre elevated bone mass study: prevalence and causes

  https://pubmed.ncbi.nlm.nih.gov/33655400/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Decreased monocyte calcium sensing receptor expression in patients with chronic kidney disease is associated with impaired monocyte ability to reduce vascular calcification

  https://pubmed.ncbi.nlm.nih.gov/33647324/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Vertebral fracture: epidemiology, impact and use of DXA vertebral fracture assessment in fracture liaison services

  https://pubmed.ncbi.nlm.nih.gov/33475820/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Bariatric Surgery and Osteoporosis

  https://pubmed.ncbi.nlm.nih.gov/33403429/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Persistence with osteoporosis treatment in patients from the Lille University Hospital Fracture Liaison Service

  https://pubmed.ncbi.nlm.nih.gov/33385615/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• Poor Bone Quality is Associated With Greater Arterial Stiffness: Insights From the UK Biobank

  https://pubmed.ncbi.nlm.nih.gov/32964541/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

• BONE PERFUSION AND ADIPOSITY BEYOND THE NECROTIC ZONE IN FEMORAL HEAD OSTEONECROSIS: A QUANTITATIVE MRI STUDY

  https://pubmed.ncbi.nlm.nih.gov/32871293/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20241016051708&v=2.18.0.post9+e462414

STRENGTH AND WEAKNESSES AT WORK

- Favorite Cell: Osteocyte

- Favorite Protein: Sclerostin

- Best technical skill: HRpQCT

- Best knowledge: Fat and bone

- Hated technique: Cell culture

- Research goal: Relationship between bone marrow fat and fragility fractures

Back to members

PERSONAL STRENGTH AND WEAKNESSES

- Favorite dish: gombo

- Favorite place to live: Lille

- Best sport skill: gym

- Free time activity: Family

- Favorite quote: you can lead a horse to water but you can't make him drink