Biography

Professor of Rheumatology at Lille University Hospital, France. He received his MD from Lille University Hospital in 2008. He has prepared and obtained his PhD thesis in 2013 on Vascular Calcification in Rheumatoid Arthritis in the INSERM U1088 laboratory at Amiens University Hospital, France. Then, he completed his postdoctoral fellowship in 2014 at the MRC Lifecourse Epidemiology Unit, University of Southampton, UK under the supervision of Professor Cyrus Cooper.

His recent research has examined Vascular Calcification in Rheumatoid Arthritis. In a review recently published in JCEM, Pr Paccou and colleagues describe the role of the Bone Marrow Fat in Skeletal Health. One of his current projects is assessing body composition changes under ustekinumab among patients with psoriatic arthritis.

Further, Pr Paccou would like to initiate a research project evaluating the bone marrow fat content in postmenopausal women with and without fragility fracture.

List of 5 Best Publications

• Bone Health Following Lifestyle-Induced Weight Loss in Individuals With Overweight/Obesity: A Narrative Review

  https://pubmed.ncbi.nlm.nih.gov/41070756/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• The Effects of Obesity and Weight Loss Interventions on Bone Health: A Narrative Review

  https://pubmed.ncbi.nlm.nih.gov/41060517/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Effects of weight-loss interventions on bone health in people living with obesity

  https://pubmed.ncbi.nlm.nih.gov/41042228/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• METHOFRACT, a methotrexate osteopathy multicentre cohort study

  https://pubmed.ncbi.nlm.nih.gov/40998522/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Clinical implications of bone marrow adiposity identified by phenome-wide association and Mendelian randomization in the UK Biobank

  https://pubmed.ncbi.nlm.nih.gov/40987763/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Prevalence and risk factors of eligibility for anti-osteoporosis medication in a cohort of men ≥50 years and postmenopausal women who had already experienced bariatric surgery

  https://pubmed.ncbi.nlm.nih.gov/40985538/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Effects of Glucagon-Like Peptide-1 receptor agonists on bone health in people living with obesity

  https://pubmed.ncbi.nlm.nih.gov/40920189/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• The Impact of Sedentary Behavior and Physical Activity on Bone Health: A Narrative Review from the Rehabilitation Working Group of the International Osteoporosis Foundation

  https://pubmed.ncbi.nlm.nih.gov/40815408/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Mortality and fracture risk in children with osteogenesis imperfecta: Results from the French nationwide hospital discharge database

  https://pubmed.ncbi.nlm.nih.gov/40803492/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Treating osteoporosis with denosumab or bisphosphonates in the long term: facts, uncertainties and assumptions. A narrative review by the clinical action group of the European Calcified Tissue Society (ECTS)

  https://pubmed.ncbi.nlm.nih.gov/40721148/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• The effects of anti-obesity medications on bone metabolism: A critical appraisal

  https://pubmed.ncbi.nlm.nih.gov/40555693/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Weight loss drugs like Wegovy could lead to an increased risk of fragility fractures in population at risk

  https://pubmed.ncbi.nlm.nih.gov/40537906/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• The relationship between bariatric surgery and risk of hip or knee replacement in severe osteoarthritis is obesity class-specific

  https://pubmed.ncbi.nlm.nih.gov/40393833/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Author Correction: Deep learning and genome-wide association meta-analyses of bone marrow adiposity in the UK Biobank

  https://pubmed.ncbi.nlm.nih.gov/40346038/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Real-world efficacy and safety of burosumab in tumor-induced osteomalacia: case series from an early access program

  https://pubmed.ncbi.nlm.nih.gov/40329993/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Patients with periprosthetic femoral fractures are older adults who are commonly diagnosed with osteoporosis

  https://pubmed.ncbi.nlm.nih.gov/40295337/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Association of hospital-initiated bone densitometry with hospitalization for fragility fracture at Lille University Hospital among adults with chronic obstructive pulmonary disease

  https://pubmed.ncbi.nlm.nih.gov/40202555/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Marrow Adiposity Content and Composition Are Not Associated With Incident Fragility Fractures in Postmenopausal Women: The ADIMOS Fracture Study

  https://pubmed.ncbi.nlm.nih.gov/40071067/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Basic and Clinical Scientists Working Together-Do We Make the Best of Both Worlds?

  https://pubmed.ncbi.nlm.nih.gov/39953279/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Management of Adverse Skeletal Effects Following Bariatric Surgery Procedures in People Living with Obesity

  https://pubmed.ncbi.nlm.nih.gov/39945979/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Deep learning and genome-wide association meta-analyses of bone marrow adiposity in the UK Biobank

  https://pubmed.ncbi.nlm.nih.gov/39747859/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Prevention and treatment of glucocorticoid-induced osteoporosis in adults: recommendations from the European Calcified Tissue Society

  https://pubmed.ncbi.nlm.nih.gov/39556468/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Is a periprosthetic fracture a fragility fracture like another?

  https://pubmed.ncbi.nlm.nih.gov/39481636/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Bone Marrow Adiposity Alterations in Postmenopausal Women With Type 2 Diabetes Are Site-Specific

  https://pubmed.ncbi.nlm.nih.gov/39381685/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Conservative Treatments in the Management of Acute Painful Vertebral Compression Fractures: A Systematic Review and Network Meta-Analysis

  https://pubmed.ncbi.nlm.nih.gov/39240564/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Bone Microarchitecture in Older Men With Type 2 Diabetes: The Importance of Bone Size

  https://pubmed.ncbi.nlm.nih.gov/39238334/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Bone health in adults with obesity before and after interventions to promote weight loss

  https://pubmed.ncbi.nlm.nih.gov/39053479/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Romosozumab versus parathyroid hormone receptor agonists: which osteoanabolic to choose and when?

  https://pubmed.ncbi.nlm.nih.gov/38938063/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Response to Pan et al

  https://pubmed.ncbi.nlm.nih.gov/38630875/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Impact of osteoporosis and osteoporosis medications on fracture healing: a narrative review

  https://pubmed.ncbi.nlm.nih.gov/38587674/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Bone mineral density T-scores comparison between obese and non-obese individuals included in a Fracture Liaison Service following a recent fragility fracture

  https://pubmed.ncbi.nlm.nih.gov/38520592/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Proton pump inhibitors, bone and phosphocalcic metabolism

  https://pubmed.ncbi.nlm.nih.gov/38458487/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• A novel deep learning method for large-scale analysis of bone marrow adiposity using UK Biobank Dixon MRI data

  https://pubmed.ncbi.nlm.nih.gov/38268780/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Characteristics of difficult-to-treat axial spondyloarthritis: Results of a real-world multicentric study

  https://pubmed.ncbi.nlm.nih.gov/38036061/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Narrative Review of Effects of Glucagon-Like Peptide-1 Receptor Agonists on Bone Health in People Living with Obesity

  https://pubmed.ncbi.nlm.nih.gov/37999750/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• The Impact of Interventional Weight Loss on Bone Marrow Adipose Tissue in People Living with Obesity and Its Connection to Bone Metabolism

  https://pubmed.ncbi.nlm.nih.gov/37960254/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Association between sarcopenia and risk of major adverse cardiac and cerebrovascular events-UK Biobank database

  https://pubmed.ncbi.nlm.nih.gov/37945290/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Characteristics Of Difficult-To-Treat Psoriatic Arthritis: A Comparative Analysis

  https://pubmed.ncbi.nlm.nih.gov/37852155/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Similarities and Differences in the Management of Patients with Osteoporotic Vertebral Fractures and Those with Rebound-Associated Vertebral Fractures Following Discontinuation of Denosumab

  https://pubmed.ncbi.nlm.nih.gov/37762815/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Glucocorticoid-induced osteoporosis: an overview with focus on its prevention and management

  https://pubmed.ncbi.nlm.nih.gov/37755658/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Relationship between bone marrow adipose tissue and kidney function in postmenopausal women

  https://pubmed.ncbi.nlm.nih.gov/37711545/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Association Between Sarcopenia and Fracture Risk in a Population From the UK Biobank Database

  https://pubmed.ncbi.nlm.nih.gov/37458535/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Myosteatosis and bone marrow adiposity are not associated among postmenopausal women with fragility fractures

  https://pubmed.ncbi.nlm.nih.gov/37404309/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Risk and management of osteoporosis due to inhaled, epidural, intra-articular or topical glucocorticoids

  https://pubmed.ncbi.nlm.nih.gov/37399940/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Usefulness of 18F-Fluorodeoxyglucose Positron Emission Tomography in Diagnosing Polymyalgia Rheumatica and Large-Vessel Vasculitis: A Case-Control Study

  https://pubmed.ncbi.nlm.nih.gov/37109181/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Effectiveness of fracture liaison services in osteoporosis

  https://pubmed.ncbi.nlm.nih.gov/37080285/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Bone Marrow Adiposity and Fragility Fractures in Postmenopausal Women: The ADIMOS Case-Control Study

  https://pubmed.ncbi.nlm.nih.gov/37017011/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Relationships between Circulating Sclerostin, Bone Marrow Adiposity, Other Adipose Deposits and Lean Mass in Post-Menopausal Women

  https://pubmed.ncbi.nlm.nih.gov/36982995/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• An Evaluation of the Implementation of the European Calcified Tissue Society Recommendations on the Prevention and Treatment of Osteoporosis Secondary to Bariatric Surgery

  https://pubmed.ncbi.nlm.nih.gov/36839365/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

• Frequency and determinants of surgical treatment in patients with uncomplicated disc-related sciatica hospitalized in the Rheumatology Department of Lille University Hospital

  https://pubmed.ncbi.nlm.nih.gov/36605997/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=12UQ-02Q1yB-OJMXqPwhVQjcWWm1ByKxO7tPOD58dGtEAPAYMf&fc=None&ff=20251016062028&v=2.18.0.post9+e462414

STRENGTH AND WEAKNESSES AT WORK

- Favorite Cell: Osteocyte

- Favorite Protein: Sclerostin

- Best technical skill: HRpQCT

- Best knowledge: Fat and bone

- Hated technique: Cell culture

- Research goal: Relationship between bone marrow fat and fragility fractures

Back to members

PERSONAL STRENGTH AND WEAKNESSES

- Favorite dish: gombo

- Favorite place to live: Lille

- Best sport skill: gym

- Free time activity: Family

- Favorite quote: you can lead a horse to water but you can't make him drink