Biography

Konstantin studied medicine at the Johannes-Gutenberg-University Mainz (Germany) from 2005-2011. He obtained his doctorate in 2011 completing a thesis on novel orthotopic animal models in bone oncology while working for Prof A. Kurth at the Department of Orthopaedics (Mainz). In parallel to starting his clinical career, where he worked at an ICU from 2012-2013, he continued his research in Mainz, focusing on several clinical trials regarding the impact of vitamin D deficiency in many orthopaedic disease patterns. In 2013, Konstantin moved to Australia to join the Bone Biology Group of Prof M. Seibel (University of Sydney) at the ANZAC Research Institute, Sydney. During a two-year post-doctoral fellowship sponsored by the German Research Foundation (DFG), he continued his research into the role of Vitamin D, particularly the Vitamin D Receptor (VDR) and vitamin D signaling in conjunction with bone metastases. Equipped with an in-depth understanding of bone and tumour biology - and the complex interactions between these systems - he returned to Germany continuing his clinical training at the Orthopaedic Department, KLH, University of Wuerzburg (Prof M. Rudert) from 2015-2017 and at the Department of Traumatology, BGU Frankfurt (Prof R. Hoffmann) from 2017-2019. Since his return from Sydney, Konstantin has set up his own research group at the Orthopaedic Center for Musculoskeletal Research, University of Wuerzburg, focusing on Vitamin D and the VDR in bone oncology. He conducted numerous clinical studies investigating the effects of vitamin D deficiency in patients with diverse orthopaedic diseases. Clinically, Konstantin is specialized in joint arthroplasty, currently working at the Orthopaedic Department, KLH, University of Wuerzburg.

List of 5 Best Publications

• Loss of the Vitamin D Receptor in Human Breast Cancer Cells Promotes Epithelial to Mesenchymal Cell Transition and Skeletal ColonizationHoras K, Zheng Y, Fong-Yee C, Macfarlane E, Manibo J, Chen Y, Qiao J, Gao M, Haydar N, McDonald MM, Croucher PI, Zhou H, Seibel MJ. https://asbmr.onlinelibrary.wiley.com/doi/full/10.1002/jbmr.3744
• High Prevalence of Vitamin D Deficiency in Patients With Bone TumorsHoras K, Maier G, Jakob F, Maus U, Kurth A, Jakuscheit A, Rudert M, Holzapfel BM.https://www.tandfonline.com/doi/full/10.1080/07357907.2017.1351985
• Loss of the vitamin D receptor in human breast and prostate cancers strongly induces cell apoptosis through downregulation of Wnt/β-catenin signalingZheng Y, Trivedi T, Lin RC, Fong-Yee C, Nolte R, Manibo J, Chen Y, Hossain M, Horas K, Dunstan C, Zhou H, Seibel MJ.https://www.nature.com/articles/boneres201723?proof=true
• High Prevalence of Vitamin D Deficiency in Patients With Bone Marrow Edema Syndrome of the Foot and AnkleHoras K, Fraissler L, Maier GS, Jakob F, Seefried L, Konrads C, Rudert M, Walcher M. https://journals.sagepub.com/doi/full/10.1177/1071100717697427?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
• Is There an Association Between Periprosthetic Joint Infection and Low Vitamin D Levels? Maier GS, Horas K, Seeger JB, Roth KE, Kurth AA, Maus U. https://link.springer.com/article/10.1007%2Fs00264-014-2338-6

STRENGTH AND WEAKNESSES AT WORK

- Areas Of Expertise: In Vivo Models, Osteoarthritis, Osteoporosis, and Bone and Cancer

- Favorite statistical software: Graphpad

- Favorite research database: Pubmed

- Best technical skill: Tumour cell inoculation

- Best knowledge: Vitamin D in bone oncology

- Hated technique: Statistics

- Research goal: Open new vistas to decrease morbidity and mortality of patients

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PERSONAL STRENGTH AND WEAKNESSES

- Favorite dish: I love BBQ

- Favorite place to live: Sydney, Australia

- Best sport skill: Swimming

- Worst performance: Ironing

- Free time activity: Travelling

- Favorite quote: There are too many good ones to quote here!