Biography
Dr Napoli received his medical degree in 2000 and completed his clinical fellowship and PhD in Metabolic Diseases at Washington University in St Louis.
He is Assistant Professor of Endocrinology at University Campus Bio-Medico of Rome and Adjunct Assistant Professor of Medicine at Washington University in St Louis. His research is funded by national and international institutions.
At the moment his group is mostly engaged on analyzing the effect of WNT pathway, inflammation, sarcopenia on bone strength in obesity and Type 2 diabetes using both human and animal models.
He is also interested on the effect of lifestyle intervention and antidiabetic medications on memory, frailty and bone fragility in diabetic patients. His research interests cover also the study of predictors and risk factors for fragility fractures in large population cohorts and their treatment through new anti-osteoporotic treatment.
He serves on the Editorial Board of JBMR, Osteoporosis International , in the Committee of Scientific Advisors of the International Osteoporosis Foundation, in the Bone academy of the ECTS. He chairs the Membership Engagement and Education Committee of the American Society of Bone and Mineral Research (ASBMR).
He has received several research awards by ASBMR, different National Institutions and he is the 2016 recipient of the Ian T Boyle award from ECTS
List of 5 Best Publications
Non-metastatic breast cancer patients discontinuing aromatase inhibitor on denosumab: what next?
https://pubmed.ncbi.nlm.nih.gov/41524787/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Consensus statement on vitamin D role in metabolic health
https://pubmed.ncbi.nlm.nih.gov/41435994/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2A Consensus Statement on the management of Vertebral Fractures in CKD stages G4-G5D
https://pubmed.ncbi.nlm.nih.gov/41313307/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2ASO Visual Abstract: Survival Benefit of Surgery Versus Oncology-Only Therapy in Artery-Involving Borderline Resectable and Locally Advanced Pancreatic Cancer
https://pubmed.ncbi.nlm.nih.gov/41238980/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2PTH-driven modulation of platelet activity via the NOX2 pathway in postsurgical hypoparathyroidism
https://pubmed.ncbi.nlm.nih.gov/41109132/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Effect of sitagliptin vs. placebo on bone mineralization in women with type 2 diabetes: the SLowDOWN (SitagLiptin in Diabetes for Osteoporosis in WomeN) randomized clinical trial
https://pubmed.ncbi.nlm.nih.gov/41088165/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Fibre-Enriched High-Carbohydrate (FEHC) Diet Modulates Inflammation Without Affecting Bone Health in Older Women With Obesity: A Randomised Clinical Trial
https://pubmed.ncbi.nlm.nih.gov/41026958/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Survival Benefit of Surgery versus Oncology-Only Therapy in Artery-Involving Borderline Resectable and Locally Advanced Pancreatic Cancer
https://pubmed.ncbi.nlm.nih.gov/40954390/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2The role of bone in whole-body energy metabolism
https://pubmed.ncbi.nlm.nih.gov/40846895/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Antiresorptive Therapy to Reduce Fracture Risk and Effects on Dental Implant Outcomes in Patients With Osteoporosis: A Systematic Review and Osteonecrosis of the Jaw Taskforce Consensus Statement
https://pubmed.ncbi.nlm.nih.gov/40335186/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Role of insulinemic and inflammatory dietary patterns on gut microbial composition and circulating biomarkers of metabolic health among older American men
https://pubmed.ncbi.nlm.nih.gov/40296253/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Platelet Function and Markers of Atherothrombotic Risk in Individuals With Parathyroid Disorders
https://pubmed.ncbi.nlm.nih.gov/40037625/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Testosterone Modulation of Muscle Transcriptomic Profile During Lifestyle Therapy in Older Men with Obesity and Hypogonadism
https://pubmed.ncbi.nlm.nih.gov/40035362/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Osteoporosis in Older Men: Informing Patient Management and Improving Health-Related Outcomes
https://pubmed.ncbi.nlm.nih.gov/39775765/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Coordinating Multidisciplinary Care - Improving Outcomes after Fragility Fractures
https://pubmed.ncbi.nlm.nih.gov/39760320/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2External Validation of the ISGPS Complexity Grading System for Minimally Invasive Pancreatoduodenectomy: Insights from the IGOMIPS registry
https://pubmed.ncbi.nlm.nih.gov/39692008/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2High-fiber diet reduces bone formation but does not affect bone microarchitecture in type 2 diabetes individuals
https://pubmed.ncbi.nlm.nih.gov/39253598/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Bone-active drugs in premenopausal women with breast cancer under hormone-deprivation therapies
https://pubmed.ncbi.nlm.nih.gov/39056237/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Risk Factors for Bone Microarchitecture Impairments in Older Men With Type 2 Diabetes-The MrOS Study
https://pubmed.ncbi.nlm.nih.gov/38994585/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Nutrition, Vitamin D, and Calcium in Elderly Patients before and after a Hip Fracture and Their Impact on the Musculoskeletal System: A Narrative Review
https://pubmed.ncbi.nlm.nih.gov/38892706/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Rethinking weight loss treatments as cardiovascular medicine in obesity, a comprehensive review
https://pubmed.ncbi.nlm.nih.gov/38833329/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Combining conventional and smartphone technologies to evaluate the psychomotor status in chronic malnutrition: A cross-sectional pilot study in sub-Saharan Africa
https://pubmed.ncbi.nlm.nih.gov/38810411/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2The Mediating Role of Kynurenine Pathway Metabolites on the Relationship Between Inflammation and Muscle Mass in Oldest-Old Men
https://pubmed.ncbi.nlm.nih.gov/38761087/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2REDISCOVER guidelines for borderline-resectable and locally advanced pancreatic cancer: management algorithm, unanswered questions, and future perspectives
https://pubmed.ncbi.nlm.nih.gov/38684573/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Consensus Statement on Vitamin D Status Assessment and Supplementation: Whys, Whens, and Hows
https://pubmed.ncbi.nlm.nih.gov/38676447/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Targeting the Hallmarks of Aging with Vitamin D: Starting to Decode the Myth
https://pubmed.ncbi.nlm.nih.gov/38542817/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Paget Disease of Bone Harboring Bone Metastatic Neuroendocrine Cancer: A Case Report
https://pubmed.ncbi.nlm.nih.gov/38506956/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Correction: Vitamin D status and supplementation before and after Bariatric Surgery: Recommendations based on a systematic review and meta‑analysis
https://pubmed.ncbi.nlm.nih.gov/38502455/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Non-invasive assessment of hepatic steatosis by ultrasound-derived fat fraction in individuals at high-risk for metabolic dysfunction-associated steatotic liver disease
https://pubmed.ncbi.nlm.nih.gov/38461408/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2More Rapid Bone Mineral Density Loss in Older Men With Diabetes: The Osteoporotic Fractures in Men (MrOS) Study
https://pubmed.ncbi.nlm.nih.gov/38407631/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2REDISCOVER International Guidelines on the Perioperative Care of Surgical Patients With Borderline-resectable and Locally Advanced Pancreatic Cancer
https://pubmed.ncbi.nlm.nih.gov/38407228/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Correction: An updated algorithm for an effective choice of continuous glucose monitoring for people with insulin-treated diabetes
https://pubmed.ncbi.nlm.nih.gov/38291319/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Correction to: Prospective minimally invasive pancreatic resections from the IGOMIPS registry: a snapshot of daily practice in Italy on 1191 between 2019 and 2022
https://pubmed.ncbi.nlm.nih.gov/38041779/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Safety and safety protocols for living donor nephrectomy in Italy
https://pubmed.ncbi.nlm.nih.gov/37940801/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Validation in type 2 diabetes of a metabolomic signature of all-cause mortality
https://pubmed.ncbi.nlm.nih.gov/37839040/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Preoperative carbohydrate antigen 19.9 level predicts lymph node metastasis in resectable adenocarcinoma of the head of the pancreas: a further plea for biological resectability criteria
https://pubmed.ncbi.nlm.nih.gov/37738016/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Abdominal adipose tissue distribution assessed by computed tomography and mortality in hospitalised patients with COVID-19: a retrospective longitudinal cohort study
https://pubmed.ncbi.nlm.nih.gov/37736820/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Spindle-cell myoepithelioma: A rare case in a finger of a 15-year-old boy
https://pubmed.ncbi.nlm.nih.gov/37714516/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2An updated algorithm for an effective choice of continuous glucose monitoring for people with insulin-treated diabetes
https://pubmed.ncbi.nlm.nih.gov/37676398/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Vitamin D status and supplementation before and after Bariatric Surgery: Recommendations based on a systematic review and meta-analysis
https://pubmed.ncbi.nlm.nih.gov/37665480/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Prospective minimally invasive pancreatic resections from the IGOMIPS registry: a snapshot of daily practice in Italy on 1191 between 2019 and 2022
https://pubmed.ncbi.nlm.nih.gov/37470915/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Biochemical Markers of Bone Fragility in Patients With Diabetes
https://pubmed.ncbi.nlm.nih.gov/37207693/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Oxidative Stress in Postmenopausal Women with or without Obesity
https://pubmed.ncbi.nlm.nih.gov/37190046/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Biochemical Markers of Bone Fragility in Patients with Diabetes. A Narrative Review by the IOF and the ECTS
https://pubmed.ncbi.nlm.nih.gov/37155585/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Relationship between Muscle Mass, Bone Density and Vascular Calcifications in Elderly People with SARS-CoV-2 Pneumonia
https://pubmed.ncbi.nlm.nih.gov/36983372/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Bone quality in endocrine diseases: determinants and clinical relevance
https://pubmed.ncbi.nlm.nih.gov/36918505/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Association of osteocalcin, osteoprotegerin, and osteopontin with cardiovascular disease and retinopathy in type 2 diabetes
https://pubmed.ncbi.nlm.nih.gov/36880127/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Diabetes and erectile dysfunction: The relationships with health literacy, treatment adherence, unrealistic optimism, and glycaemic control
https://pubmed.ncbi.nlm.nih.gov/36823962/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Vitamin D and malabsorptive gastrointestinal conditions: A bidirectional relationship?
https://pubmed.ncbi.nlm.nih.gov/36813995/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2Gluten-Free Diet and Metabolic Syndrome: Could Be a Not Benevolent Encounter?
https://pubmed.ncbi.nlm.nih.gov/36771334/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1RwSy84-6Ztx-cjsbd7ygw93HuSjhUYD6yIVIbwBadoDe_zciH&fc=None&ff=20260113035929&v=2.18.0.post22+67771e2