First Name: Steve
Last Name: Stegen
Member Since: May 2020
City: Leuven
Institution: KU Leuven, Belgium

Biography

Dr. Steve Stegen is a postdoctoral research fellow in the Clinical & Experimental Endocrinology lab (Prof. Geert Carmeliet) at the KU Leuven in Leuven, Belgium. He currently holds a senior postdoctoral research grant from the Research Foundation Flanders (FWO).

Steve completed his MSc in Biomedical Sciences in 2010 at the KU Leuven, where he studied the effect of posttranslational modifications on chemokine activity. During his PhD in the lab of Prof. Geert Carmeliet, he investigated the role of hypoxia signaling in skeletal cells and its application for bone tissue engineering. It was then that he developed his passion for bone research and cell metabolism. In 2016, Steve got awarded with an FWO junior postdoctoral fellowship to investigate the role of glutamine metabolism in skeletal cells.

Steve’s current research focusses on the in-depth characterization of the metabolic needs of healthy and diseased skeletal cells. His expertise includes preclinical mouse models for fracture healing and osteoporosis, bone imaging/histology, primary skeletal cell isolation and metabolomics.

Steve is a member of several scientific societies such as ECTS and ASBMR, and he presented his findings at international meetings (ASBMR, Gordon Research Seminar). His work received several awards, including the ASBMR Young Investigator Award in 2016.

STRENGTH AND WEAKNESSES AT WORK

- Favorite Cell: Chondrocyte
- Favorite Protein: HIF-1
- Best technical skill: Western blot
- Best knowledge: Skeletal cell metabolism
- Hated technique: ChIP
- Research goal: To study the metabolic regulation of skeletal cell function during bone development, homeostasis and disease.
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PERSONAL STRENGTH AND WEAKNESSES

- Favorite dish: Pizza margherita
- Favorite place to live: Leuven
- Best sport skill: Cycling
- Worst performance: Running
- Free time activity: Sports - playing with my children (that fills up about everything)
- Favorite quote: ‘Wonder is the seed of knowledge‘ (Francis Bacon)