Academic Title: Associate professor
First Name: Thomas
Last Name: Funck-Brentano
Academic Degree: MD PhD
Member Since: 2016
City: Paris
Institution: Université de Paris
Contact:

Biography

Thomas Funck-Brentano is a clinical rheumatologist dealing with bone diseases and arthritis with a preclinical background.

He trained in University Paris Diderot and defendend his PhD in 2013 on the role of the Wnt signaling pathway in the subchondral bone in preclinical models of osteoarthritis.

He was president of the “Young Rheumatologists” section of the French Society of Rheumatology (2011-2013). He was then assistant professor in the department of Rheumatology in Hôpital Lariboisière in Paris (2012-2016) were he got particularly interested in managing bone diseases, such as osteoporosis, bone health of transplanted patients or end-stage renal failure and rare bone diseases.

He has recently moved to the University of Gothenburg (Sweden) in Pr Claes Ohlsson’s group to enhance his skills in translational research in bone diseases. His project on the functional studies of NOTUM as a regulator of cortical bone mass was granted by Sweden’s Innovation Agency Vinnova for a two-year fellowship.

He is also involved in clinical projects on the link between bone and cardiometabolic diseases and osteoarthritis using various large databases.

Awards

  • 20/09/2017ASBMR 2017 Fund for Research and Education Young Investigator Award

Grants

  • 01/12/2017EU H2020 Marie Sklodowska Curie Individual Fellowship

List of 5 Best Publications

  • Causal Factors for Knee, Hip, and Hand Osteoarthritis: A Mendelian Randomization Study in the UK Biobank.Funck-Brentano T, Nethander M, Movérare-Skrtic S, Richette P, Ohlsson Chttps://doi.org/10.1002/art.40928
  • What are the predictors of clinical success after percutaneous vertebroplasty for osteoporotic vertebral fractures?Denoix E, Viry F, Ostertag A, Parlier-Cuau C, Laredo JD, Cohen-Solal M, Bousson V, Funck-Brentano T.https://doi.org/10.1007/s00330-017-5274-1
  • Porcupine inhibitors impair trabecular and cortical bone mass and strength in mice.Funck-Brentano T, Nilsson KH, Brommage R, Henning P, Lerner UH, Koskela A, Tuukkanen J, Cohen-Solal M, Movérare-Skrtic S, Ohlsson C.https://doi.org/10.1530/JOE-18-0153
  • Dkk-1-mediated inhibition of Wnt signaling in bone ameliorates osteoarthritis in mice.Funck-Brentano T, Bouaziz W, Marty C, Geoffroy V, Hay E, Cohen-Solal M.https://doi.org/10.1002/art.38799
  • Subchondral bone and osteoarthritis.Funck-Brentano T, Cohen-Solal M.https://doi.org/10.1097/BOR.0000000000000181

STRENGTH AND WEAKNESSES AT WORK

- Year Of Promotion: 2018
- Areas Of Expertise: Bone Density, Bone Strength, Clinical Medicine, Histomorphometry, In Vivo Models, Osteoarthritis, Osteoporosis, and Rare Bone Diseases
- Favorite statistical software: SPSS
- Favorite research database: Pubmed
- Favorite technique: µCT
- Favorite Protein: Dkk1
- Best technical skill: Patients
- Best knowledge: Subchondral bone
- Hated technique: Western Blot
- Research goal: Find new therapies for the prevention of osteoporosis and improve the quality of life of patients with rare bone diseases
Back to members

PERSONAL STRENGTH AND WEAKNESSES

- Favorite dish: Osso bucco
- Favorite place to live: Grenoble (France)
- Best sport skill: Ski touring
- Worst performance: Cooking
- Free time activity: Music
- Favorite quote: Eternity is a long time, especially towards the end, Woody Allen